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Academic Background:
Ph.D. Kanpur
University, Kanpur, India,
1987
Research Interests:
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Effect of drug and alcohol abuse on pathogenesis of AIDS.
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Identification of target of immune responses in HIV-1 during
natural infection
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Compartmentalization of HIV during natural infection
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Vaccine
approaches in monkey model of AIDS
Research Grants:
5R01AA015045-03
(Kumar) Alcohol and AIDS: Pathogenesis and Immunity in Macaque
5R21AI059361-02 (Kumar) Immune Targets during Natural Dengue
Infection
Lab Members:
Ashish S. Verma,
Ph.D.
Grissell Tirado, Ph.D.
Aseem Umesh, Ph.D.
Antonio Perez Casanova, M.S.
Research Publications (2006 only):
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Kumar R,
Orsoni S, Norman L, Verma AS, Tirado G, Giavedoni LD,
Staprans S, Miller GM, Buch SJ, Kumar A. (2006).
Chronic morphine exposure causes pronounced virus
replication in cerebral compartment and accelerated onset of
AIDS in SIV/SHIV-infected Indian rhesus macaques. Virology.
Online publication PMID: 16876224. |
| Noel
RJ Jr, Marrero-Otero Z, Kumar R, Chompre-Gonzalez GS, Verma
AS, Kumar A. (2006) Correlation between SIV Tat
evolution and AIDS progression in cerebrospinal fluid of
morphine-dependent and control macaques infected with SIV
and SHIV. Virology. 349:440-52. |
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Tirado G, Kumar A. (2006) Evolution of SIV envelope
in morphine-dependent rhesus macaques with rapid disease
progression. AIDS Res Hum Retroviruses. 22:114-9. |
| Noel
RJ Jr, Kumar A. (2006) Virus replication and disease
progression inversely correlate with SIV tat evolution in
morphine-dependent and SIV/SHIV-infected Indian rhesus
macaques. Virology. 346:127-38. |
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Dhillon NK, Dhillon S, Chebloune Y, Pinson D, Villinger F,
Kumar A, Narayan O, Buch S. (2006) Therapy of "SHIV"
infected macaques with liposomes delivering antisense
interleukin-4 DNA. AIDS. 20:1125-30. |
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Singh DP, Kubo E, Takamura Y, Shinohara T, Kumar A,
Chylack LT Jr, Fatma N. (2006) DNA binding domains and
nuclear localization signal of LEDGF: contribution of two
helix-turn-helix (HTH)-like domains and a stretch of 58
amino acids of the N-terminal to the trans-activation
potential of LEDGF. J Mol Biol. 355:379-94. |
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Norman LR and Kumar A. (2006) Neuropscyhological
Complications of HIV Disease and Substances of Abuse. Am. J
Inf. Dis. 2:115-124. |
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Rivera-Amill V, Noel RJ, Orsoni S, Tirado G, Garcia J, Buch
SJ and Kumar A. (2006) The variable region 4 of SIV
envelope correlates with rapid disease progression in
morphine-exposed macaques infected with SIV/SHIV. Virology.
In press. |
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Noel RJ
Jr, Toro-Bahamonde A, Marrero-Otaro Z, Orsoni S, Verma AS,
Kumar R, Kumar A. (2006) Lack of Correlation Between
SIV-Nef Evolution and Rapid Disease Progression in
Morphine-dependent Non-Human Primate model of AIDS. AIDS Res
Hum Retroviruses. 22: |
| Noel
RJ and Kumar A. (2006) SIV Vpr evolution is inversely
related to disease progression in a morphine-dependent
rhesus macaque model of AIDS. Submitted. |
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